Organic Reaction Chemistry, Review I (Flash, P.; Bendall, V.)

Organic Chemistry I Laboratory

The problem you need to solve is to determine the identity of the individual components from your mixture. You will use several different techniques today and compare your experimental results to those of known standards. From this data you should be able to identify all of the components of your original mixture. Keep careful records of your observations and your interpretation of spectra so t...

Organic Chemistry I Laboratory

For many years the dehydration of 2-methylcyclohexanol to a mixture of alkenes has been carried out in college organic chemistry labs to demonstrate the application of Zaitzev’s rule and the occurrence of the E1 reaction mechanism in alcohol dehydration reactions. In 1994 David Todd, then a chemistry professor at Pomona College, was distilling the product alkenes out of the reaction mixture whe...

The Sonogashira reaction: a booming methodology in synthetic organic chemistry.

3.7. Palladium Nanoparticles as Catalysts 888 3.8. Other Transition-Metal Complexes 888 3.9. Transition-Metal-Free Reactions 889 4. Applications 889 4.1. Alkynylation of Arenes 889 4.2. Alkynylation of Heterocycles 891 4.3. Synthesis of Enynes and Enediynes 894 4.4. Synthesis of Ynones 896 4.5. Synthesis of Carbocyclic Systems 897 4.6. Synthesis of Heterocyclic Systems 898 4.7. Synthesis of Nat...

Reaction Mechanisms in Organic Synthesis Postgraduate Chemistry Series

Reaction intermediates in organic chemistry — The “big picture”1

An overview of the discovery of reaction intermediates and associated concepts in physical organic chemistry is presented. Particular attention is paid to chronology of ideas, frequency of occurrence of reaction intermediates in the library of organic reactions used in organic synthesis, and the lexicon of scientific terms used in the language of physical organic chemistry. General logic decisi...